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Hypereosinophilic Syndrome (Loeffler Endocarditis) Summary

429 relevant articles (39 outcomes, 17 trials/studies) found for this Disease

Description: A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.

Also Known As: Loeffler Endocarditis; Idiopathic Hypereosinophilic Syndrome; Endocarditis, Loeffler; Leukemia, Eosinophilic; Endocarditis, Loefflers Show All >>

Key Drugs and Agents for Hypereosinophilic Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. imatinib (Gleevec) : 25 outcomes 2 studies in 87 results : FDA 2
  2. Interferon-alpha (Interferon Alfa) : 6 outcomes 1 study in 35 results : FDA 1
  3. mepolizumab : 2 outcomes 2 studies in 8 results : IBA
  4. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor) : 2 outcomes in 15 results : IBA
  5. Phosphotransferases (Kinase) : 2 outcomes in 11 results : IBA
  6. Prednisone (Sone) : 2 outcomes in 7 results : FDA 118 Generic
  7. Interleukin-5 (Interleukin 5) : 1 outcome 1 study in 31 results : IBA
  8. Monoclonal Antibodies : 1 outcome 1 study in 3 results : IBA
  9. Protein-Tyrosine Kinases (Tyrosine Kinase) : 1 outcome in 34 results : IBA
  10. Hydroxyurea (Hydrea) : 1 outcome in 15 results : FDA 6 Generic
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Diseases Related to Hypereosinophilic Syndrome

  1. Eosinophilia
  2. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
  3. Chromosome Aberrations (Chromosome Abnormalities)
  4. Trisomy
  5. Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
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Key Therapies for Hypereosinophilic Syndrome

Efficacy Chart >>
  1. Stem Cell Transplantation : 1 outcome in 3 results
  2. Transplants (Transplant) : 1 outcome in 3 results
  3. Aftercare (After-Treatment) : 1 outcome in 3 results
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 11 results
  5. Drug Therapy (Chemotherapy) : 5 results
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