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CD45 Antigens (CD45 Antigen) Summary

Description: High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain a cytoplasmic protein tyrosine phosphatase activity which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. The CD45 antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.

Also Known As: CD45 Antigen; Antigens, CD45; 2H4 Antigens; B220 Antigen; B220 Antigens Show All >>

Networked: 289 relevant articles (6 outcomes, 31 trials/studies) for this Bio-Agent

Key Diseases for which CD45 Antigens is Relevant

  1. Lymphoma (Lymphomas) : 3 outcomes 4 studies in 40 results
  2. Melanoma (Melanoma, Malignant) : 1 outcome 1 study in 13 results
  3. Type 1 Diabetes Mellitus (Autoimmune Diabetes) : 1 outcome 1 study in 4 results
  4. Carcinoma (Carcinomatosis) : 1 outcome in 16 results
  5. Inflammation : 1 outcome in 7 results
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Drugs Related to CD45 Antigens

  1. CD45 Antigens (CD45 Antigen)
  2. Keratins (Keratin)
  3. Antibodies
  4. S100 Proteins (S 100 Protein)
  5. Muramidase (Lysozyme)
  6. von Willebrand Factor
  7. Biological Markers (Surrogate Marker)
  8. Pancreatic Elastase (Elastase)
  9. Glycoproteins (Glycoprotein)
  10. Ethanol (Ethyl Alcohol)
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Therapies Related to CD45 Antigens

  1. Radioimmunotherapy
  2. Homologous Transplantation (Allograft)
  3. Heterologous Transplantation (Xenotransplantation)
  4. Microspheres (Microsphere)
  5. Immunotherapy

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