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Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) Summary

338 relevant articles (3 outcomes, 37 trials/studies) found for this Disease

Description: A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)

Also Known As: Progressive External Ophthalmoplegia; CPEO; Ocular Muscular Dystrophy; Ophthalmoplegia, Chronic Progressive External; Graefe's Disease Show All >>

Key Drugs and Agents for Chronic Progressive External Ophthalmoplegia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Mitochondrial DNA (mtDNA) : 1 outcome 22 studies in 218 results : IBA
  2. coenzyme Q10 (CoQ10) : 1 outcome 1 study in 4 results : IBA
  3. Ubiquinone : 1 outcome 1 study in 1 result : IBA
  4. Electron Transport Complex IV (Cytochrome c Oxidase) : 4 studies in 23 results : IBA
  5. DNA (Deoxyribonucleic Acid) : 2 studies in 20 results : IBA
  6. Ile Transfer RNA : 2 studies in 5 results : IBA
  7. Tyr Transfer RNA : 2 studies in 4 results : IBA
  8. Retinaldehyde (Retinal) : 1 study in 23 results : IBA
  9. Transfer RNA (tRNA) : 1 study in 12 results : IBA
  10. Leu Transfer RNA : 1 study in 9 results : IBA
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Diseases Related to Chronic Progressive External Ophthalmoplegia

  1. Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia)
  2. Syndrome
  3. Mitochondrial Myopathies (Mitochondrial Myopathy)
  4. Mitochondrial Diseases (Mitochondrial Disease)
  5. Lactic Acidosis
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Key Therapies for Chronic Progressive External Ophthalmoplegia

Efficacy Chart >>
  1. Mechanical Ventilators (Ventilator) : 1 study in 2 results
  2. Lasers (Laser) : 1 study in 2 results
  3. Heart Transplantation (Grafting, Heart) : 1 result
  4. Exercise (Aerobic Exercise) : 1 result
  5. Suture Techniques : 1 result
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