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Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy) Summary

Description: A heterogenous group of disorders characterized by alterations of mitochondrial metabolism that result in muscle and nervous system dysfunction. These are often multisystemic and vary considerably in age at onset (usually in the first or second decade of life), distribution of affected muscles, severity, and course. (From Adams et al., Principles of Neurology, 6th ed, pp984-5)

Also Known As: Mitochondrial Encephalomyopathy; Encephalomyopathy, Mitochondrial; Encephalomyopathies, Mitochondrial

Networked: 401 relevant articles (5 outcomes, 27 trials/studies) for this Disease

Key Drugs and Agents for Mitochondrial Encephalomyopathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. coenzyme Q10 (CoQ10) : 1 outcome 3 studies in 13 results : IBA
  2. Leu Transfer RNA : 1 outcome 2 studies in 38 results : IBA
  3. idebenone : 1 outcome 2 studies in 4 results : IBA
  4. Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase) : 1 outcome in 5 results : IBA
  5. Creatine : 1 outcome in 2 results : IBA
  6. Cytochromes c (Cytochrome c) : 1 outcome in 1 result : IBA
  7. Thiamine Pyrophosphate : 1 outcome in 1 result : IBA
  8. Flavin Mononucleotide (FMN) : 1 outcome in 1 result : IBA
  9. lamotrigine (Lamictal) : 1 outcome in 1 result : FDA 33 Generic
  10. thiamine pyrophosphate drug combination flavin mononucleotide cytochrome C : 1 outcome in 1 result : IBA
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Diseases Related to Mitochondrial Encephalomyopathies

  1. Lactic Acidosis
  2. Stroke (Strokes)
  3. Status Epilepticus (Complex Partial Status Epilepticus)
  4. Myoclonic Epilepsies (Myoclonic Encephalopathy)
  5. Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia)
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Key Therapies for Mitochondrial Encephalomyopathies

Efficacy Chart >>
  1. Intravenous Injections : 1 outcome in 1 result
  2. Anesthesia : 6 results
  3. Intravenous Anesthesia : 2 results
  4. General Anesthesia : 2 results
  5. Micro-Electrical-Mechanical Systems : 1 result
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