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Advanced Glycosylation End Products Summary

Description: Products derived from the nonenzymatic reaction of glucose and proteins in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of diabetes mellitus.

Also Known As: Glycosylation End Products, Advanced; Advanced Glycation End Products; Glycation End Products, Advanced

Networked: 2322 relevant articles (22 outcomes, 156 trials/studies) for this Bio-Agent

Key Diseases for which Advanced Glycosylation End Products is Relevant

  1. Inflammation : 3 outcomes 19 studies in 223 results
  2. Diabetic Nephropathies (Diabetic Nephropathy) : 2 outcomes 12 studies in 221 results
  3. Chronic Kidney Failure (Chronic Renal Failure) : 2 outcomes 6 studies in 54 results
  4. Diabetic Angiopathies (Diabetic Angiopathy) : 2 outcomes 3 studies in 95 results
  5. Atherosclerosis : 1 outcome 9 studies in 180 results
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Drugs Related to Advanced Glycosylation End Products

  1. Nitric Oxide (Nitrogen Monoxide)
  2. pentosidine
  3. Ligands
  4. polyol
  5. pimagedine (aminoguanidine)
  6. Calcium
  7. Angiotensin II
  8. 4-hydroxy-2-nonenal (4-hydroxynonenal)
  9. iodonitrotetrazolium (INT)
  10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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Therapies Related to Advanced Glycosylation End Products

  1. Renal Dialysis (Hemodialysis)
  2. Peritoneal Dialysis
  3. Continuous Ambulatory Peritoneal Dialysis (CAPD)
  4. Transplants (Transplant)
  5. Artificial Respiration (Mechanical Ventilation)
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