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Advanced Glycosylation End Products
Summary
Description:
Products derived from the nonenzymatic reaction of glucose and proteins in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of diabetes mellitus.
Also Known As:
Glycosylation End Products, Advanced; Advanced Glycation End Products; Glycation End Products, Advanced
Networked: 2322
relevant articles (22 outcomes,
156 trials/studies)
for this Bio-Agent
Key Diseases for which Advanced Glycosylation End Products is
Relevant
-
Inflammation
:
3 outcomes 19 studies in 223 results
-
Diabetic Nephropathies (Diabetic Nephropathy)
:
2 outcomes 12 studies in 221 results
-
Chronic Kidney Failure (Chronic Renal Failure)
:
2 outcomes 6 studies in 54 results
-
Diabetic Angiopathies (Diabetic Angiopathy)
:
2 outcomes 3 studies in 95 results
-
Atherosclerosis
:
1 outcome 9 studies in 180 results
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Drugs Related to Advanced Glycosylation End Products
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Nitric Oxide (Nitrogen Monoxide)
-
pentosidine
-
Ligands
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polyol
-
pimagedine (aminoguanidine)
-
Calcium
-
Angiotensin II
-
4-hydroxy-2-nonenal (4-hydroxynonenal)
-
iodonitrotetrazolium (INT)
-
Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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Therapies Related to Advanced Glycosylation End Products
-
Renal Dialysis (Hemodialysis)
-
Peritoneal Dialysis
-
Continuous Ambulatory Peritoneal Dialysis (CAPD)
-
Transplants (Transplant)
-
Artificial Respiration (Mechanical Ventilation)
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