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Acute Liver Failure (Fulminant Hepatic Failure) Summary

Description: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Also Known As: Fulminant Hepatic Failure; Liver Failure, Acute; Fulminating Liver Failure; Hepatic Failure, Acute; Acute Hepatic Failure Show All >>

Networked: 4657 relevant articles (276 outcomes, 451 trials/studies) for this Disease

Key Drugs and Agents for Acute Liver Failure

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Galactosamine : 24 outcomes 52 studies in 247 results : IBA
  2. Acetaminophen (Paracetamol) : 21 outcomes 41 studies in 504 results : FDA 409 Generic
  3. Acetylcysteine (Siran) : 9 outcomes 10 studies in 60 results : FDA 17 Generic
  4. Thioacetamide (Thioacetamid) : 5 outcomes 18 studies in 80 results : IBA
  5. Carbon Tetrachloride (Tetrachloromethane) : 5 outcomes 7 studies in 47 results : IBA
  6. Cytokines : 5 outcomes 2 studies in 48 results : IBA
  7. Charcoal (Charbon) : 4 outcomes 3 studies in 31 results : IBA
  8. Alprostadil (Muse) : 4 outcomes 2 studies in 11 results : FDA 8 Generic
  9. Lactic Acid : 3 outcomes 6 studies in 43 results : FDA 4 Generic
  10. Adenosine Triphosphate (ATP) : 3 outcomes 3 studies in 11 results : IBA
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Diseases Related to Acute Liver Failure

  1. Hepatitis
  2. End Stage Liver Disease
  3. Hepatic Encephalopathy
  4. Fibrosis (Cirrhosis)
  5. Liver Diseases (Liver Disease)
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Key Therapies for Acute Liver Failure

Efficacy Chart >>
  1. Liver Transplantation : 66 outcomes 44 studies in 1199 results
  2. Transplantation (Transplant Recipients) : 37 outcomes 45 studies in 454 results
  3. Artificial Liver (Bioartificial Liver) : 22 outcomes 28 studies in 222 results
  4. Transplants (Transplant) : 10 outcomes 19 studies in 380 results
  5. Drug Therapy (Chemotherapy) : 6 outcomes in 42 results
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