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beta-Thalassemia (Cooley's Anemia) Summary

Description: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

Also Known As: Cooley's Anemia; Thalassemia Major; Erythroblastic Anemia; Mediterranean Anemia; Thalassemia Minor Show All >>

Networked: 4155 relevant articles (158 outcomes, 561 trials/studies) for this Disease

Key Drugs and Agents for beta-Thalassemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Iron : 41 outcomes 101 studies in 725 results : IBA
  2. Deferoxamine (Desferal) : 15 outcomes 41 studies in 214 results : FDA 5 Generic
  3. Hemoglobins (Hemoglobin) : 10 outcomes 44 studies in 483 results : IBA
  4. deferiprone (CP20) : 10 outcomes 24 studies in 114 results : IBA
  5. Fetal Hemoglobin (Hemoglobin F) : 10 outcomes 23 studies in 224 results : IBA
  6. deferasirox : 10 outcomes 19 studies in 78 results : FDA 1
  7. Hydroxyurea (Hydrea) : 10 outcomes 14 studies in 83 results : FDA 6 Generic
  8. DNA (Deoxyribonucleic Acid) : 5 outcomes 19 studies in 227 results : IBA
  9. Ferritins (Ferritin) : 4 outcomes 33 studies in 145 results : IBA
  10. Globins : 4 outcomes 30 studies in 266 results : IBA
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Diseases Related to beta-Thalassemia

  1. Iron Overload
  2. Sickle Cell Anemia (Hemoglobin S Disease)
  3. Anemia
  4. Hemoglobinopathies
  5. Heart Failure
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Key Therapies for beta-Thalassemia

Efficacy Chart >>
  1. Chelation Therapy (Therapy, Chelation) : 17 outcomes 20 studies in 166 results
  2. Splenectomy : 6 outcomes 15 studies in 141 results
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 5 outcomes 12 studies in 101 results
  4. Hematopoietic Stem Cell Transplantation : 3 outcomes 3 studies in 46 results
  5. Stem Cell Transplantation : 3 outcomes 2 studies in 31 results
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