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beta-Thalassemia (Cooley's Anemia) Summary

3076 relevant articles (92 outcomes, 373 trials/studies) found for this Disease

Description: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

Also Known As: Cooley's Anemia; Thalassemia Major; Erythroblastic Anemia; Mediterranean Anemia; Thalassemia Minor Show All >>

Key Drugs and Agents for beta-Thalassemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Iron (Serum Iron Level) : 18 outcomes 55 studies in 447 results : IBA
  2. Deferoxamine (Desferal) : 12 outcomes 28 studies in 165 results : FDA 4 Generic
  3. Hemoglobins (Hemoglobin) : 9 outcomes 36 studies in 389 results : IBA
  4. Fetal Hemoglobin (Hemoglobin F) : 9 outcomes 17 studies in 179 results : IBA
  5. deferiprone (CP20) : 8 outcomes 15 studies in 63 results : IBA
  6. Globins (Globin) : 7 outcomes 69 studies in 676 results : IBA
  7. Hydroxyurea (Hydrea) : 6 outcomes 9 studies in 38 results : FDA 6 Generic
  8. DNA (Deoxyribonucleic Acid) : 4 outcomes 15 studies in 207 results : IBA
  9. Vitamin E : 3 outcomes 3 studies in 15 results : FDA 12
  10. deferasirox : 2 outcomes 7 studies in 13 results : FDA 1
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Diseases Related to beta-Thalassemia

  1. Iron Overload
  2. Anemia
  3. Sickle Cell Anemia (Hemoglobin S Disease)
  4. Thalassemia
  5. Hemoglobinopathies
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Key Therapies for beta-Thalassemia

Efficacy Chart >>
  1. Chelation Therapy (Therapy, Chelation) : 10 outcomes 11 studies in 98 results
  2. Splenectomy : 5 outcomes 8 studies in 99 results
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 4 outcomes 11 studies in 88 results
  4. Stem Cell Transplantation : 2 outcomes 1 study in 13 results
  5. Erythrocyte Transfusion : 2 outcomes in 4 results
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