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Cryptococcal Meningitis Summary

Description: Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)

Also Known As: Meningitis, Cryptococcal; Cerebral Cryptococcosis; Cerebral Cryptococcoses; Cerebral Cryptococcoses, Granulomous; Cerebral Cryptococcosis, Granulomous; Cryptococcal Meningitides; Cryptococcoses, Cerebral; Cryptococcoses, Granulomous Cerebral; Cryptococcosis, Cerebral; Cryptococcosis, Granulomous Cerebral; Granulomous Cerebral Cryptococcoses; Meningitides, Cryptococcal; Torulomas; Granulomous Cerebral Cryptococcosis; Toruloma

Networked: 676 relevant articles (78 outcomes, 88 trials/studies) for this Disease

Key Drugs and Agents for Cryptococcal Meningitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Fluconazole (Zonal) : 33 outcomes 31 studies in 176 results : FDA 41 Generic
  2. Amphotericin B (Amphotericin) : 28 outcomes 31 studies in 192 results : FDA 12 Generic
  3. Flucytosine (Ancobon) : 10 outcomes 18 studies in 96 results : FDA 1
  4. Itraconazole (Sporanox) : 8 outcomes 10 studies in 26 results : FDA 6 Generic
  5. liposomal amphotericin B : 7 outcomes 6 studies in 26 results : FDA 2
  6. Antigens : 3 outcomes 3 studies in 66 results : IBA
  7. Ketoconazole (Nizoral) : 3 outcomes 1 study in 10 results : FDA 20 Generic
  8. phospholipid emulsion soybean oil (Intralipid) : 2 outcomes 1 study in 5 results : IBA
  9. Deoxycholic Acid (Sodium Deoxycholate) : 2 outcomes 1 study in 3 results : IBA
  10. Latex : 2 outcomes in 23 results : IBA
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Diseases Related to Cryptococcal Meningitis

  1. Acquired Immunodeficiency Syndrome (AIDS)
  2. Infection
  3. Candidiasis (Moniliasis)
  4. Aspergillosis
  5. Cryptococcosis
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Key Therapies for Cryptococcal Meningitis

Efficacy Chart >>
  1. Transplants (Transplant) : 1 outcome 2 studies in 17 results
  2. Intraventricular Infusions : 1 outcome in 2 results
  3. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome in 2 results
  4. Intravenous Injections : 1 outcome in 1 result
  5. Highly Active Antiretroviral Therapy (HAART) : 4 studies in 28 results
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