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Cerebral Toxoplasmosis Summary

Description: Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)

Also Known As: Toxoplasmosis, Cerebral; Central Nervous System Toxoplasmosis; Toxoplasmoses, Cerebral; Toxoplasmosis, Intracranial; Intracranial Toxoplasmosis Show All >>

Networked: 236 relevant articles (15 outcomes, 20 trials/studies) for this Disease

Key Drugs and Agents for Cerebral Toxoplasmosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Pyrimethamine (Daraprim) : 6 outcomes 3 studies in 39 results : FDA 2
  2. Sulfadiazine (Sulphadiazine) : 3 outcomes 1 study in 29 results : FDA 8
  3. Clindamycin (Cleocin) : 2 outcomes 2 studies in 12 results : FDA 19 Generic
  4. Trimetrexate (JB11) : 1 outcome 1 study in 1 result : FDA 1
  5. Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole) : 1 outcome in 16 results : FDA 6 Generic
  6. Zidovudine (Retrovir) : 1 outcome in 2 results : FDA 42 Generic
  7. Doxycycline (Vibramycin) : 1 outcome in 2 results : FDA 23 Generic
  8. Roxithromycin : 1 outcome in 1 result : IBA
  9. Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase) : 1 outcome in 1 result : IBA
  10. TNFR-Fc fusion protein (etanercept) : 1 outcome in 1 result : FDA 2
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Diseases Related to Cerebral Toxoplasmosis

  1. Acquired Immunodeficiency Syndrome (AIDS)
  2. HIV Infections (HIV Infection)
  3. Hypersensitivity (Allergy)
  4. Pneumocystis Infections
  5. Toxoplasmosis
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Key Therapies for Cerebral Toxoplasmosis

Efficacy Chart >>
  1. Aftercare (After-Treatment) : 2 outcomes in 3 results
  2. Transplants (Transplant) : 1 study in 14 results
  3. Organ Transplantation : 1 study in 1 result
  4. Highly Active Antiretroviral Therapy (HAART) : 11 results
  5. Transplantation (Transplant Recipients) : 8 results
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