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Cerebral Malaria Summary

Description: A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)

Also Known As: Malaria, Cerebral; Meningitis, Malaria; Malaria Meningitis

Networked: 984 relevant articles (66 outcomes, 130 trials/studies) for this Disease

Key Drugs and Agents for Cerebral Malaria

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. artemether : 11 outcomes 11 studies in 30 results : FDA 1
  2. Quinine (Quinson) : 10 outcomes 22 studies in 85 results : FDA 2
  3. artemisinine (artemisinin) : 7 outcomes 3 studies in 27 results : IBA
  4. artesunate : 5 outcomes 6 studies in 22 results : IBA
  5. Antibodies : 3 outcomes 4 studies in 28 results : IBA
  6. Chloroquine (Aralen) : 3 outcomes 3 studies in 36 results : FDA 1 Generic
  7. arteether (artemotil) : 3 outcomes 3 studies in 7 results : IBA
  8. Mefloquine (Lariam) : 3 outcomes 2 studies in 16 results : FDA 6 Generic
  9. atorvastatin (Lipitor) : 3 outcomes 1 study in 3 results : FDA 2
  10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 2 outcomes 7 studies in 67 results : IBA
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Diseases Related to Cerebral Malaria

  1. Malaria
  2. Parasitemia
  3. Infection
  4. Coma (Comas)
  5. Shock
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Key Therapies for Cerebral Malaria

Efficacy Chart >>
  1. Enteral Nutrition (Feeding, Tube) : 1 outcome 1 study in 1 result
  2. Intranasal Administration : 1 outcome 1 study in 1 result
  3. Drug Therapy (Chemotherapy) : 1 outcome in 11 results
  4. Chelation Therapy (Therapy, Chelation) : 1 outcome in 5 results
  5. Renal Dialysis (Hemodialysis) : 1 outcome in 4 results
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