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Alagille Syndrome (Alagille-Watson Syndrome) Summary

96 relevant articles (3 outcomes, 6 trials/studies) found for this Disease

Description: A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).

Also Known As: Alagille-Watson Syndrome; Alagille Syndrome 1; Alagille Syndrome 2; Cholestasis with Peripheral Pulmonary Stenosis; Hepatic Ductular Hypoplasia, Syndromatic Show All >>

Key Drugs and Agents for Alagille Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Vitamins : 1 outcome in 1 result : IBA
  2. terthienyl (alpha-T) : 1 outcome in 1 result : IBA
  3. Cholesterol : 2 studies in 8 results : IBA
  4. Cholestyramine (Questran) : 2 studies in 3 results : FDA 18 Generic
  5. Apolipoproteins : 2 studies in 2 results : IBA
  6. Lipoproteins (Lipoprotein) : 1 study in 5 results : IBA
  7. Lecithins : 1 study in 2 results : IBA
  8. Neprilysin (Neutral Endopeptidase) : 1 study in 2 results : IBA
  9. Transferases : 1 study in 2 results : IBA
  10. CD13 Antigens (Alanine Aminopeptidase) : 1 study in 1 result : IBA
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Diseases Related to Alagille Syndrome

  1. Cholestasis
  2. Liver Diseases (Liver Disease)
  3. Intrahepatic Cholestasis
  4. Gallstones (Gallstone)
  5. Hypercholesterolemia
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Key Therapies for Alagille Syndrome

Efficacy Chart >>
  1. Liver Transplantation : 1 outcome 1 study in 24 results
  2. Transplants (Transplant) : 5 results
  3. Transplantation (Transplant Recipients) : 4 results
  4. Anesthesia : 3 results
  5. Enteral Nutrition (Feeding, Tube) : 2 results
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