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Cerebral Amyloid Angiopathy (Congophilic Angiopathy) Summary

Description: A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005)

Also Known As: Congophilic Angiopathy; Angiopathy, Cerebral Amyloid; Angiopathy, Congophilic; Cerebral Amyloid Angiopathies; Congophilic Angiopathies Show All >>

Networked: 794 relevant articles (7 outcomes, 45 trials/studies) for this Disease

Key Drugs and Agents for Cerebral Amyloid Angiopathy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Amyloid (Amyloid Fibrils) : 5 outcomes 17 studies in 396 results : IBA
  2. Amyloid beta-Peptides : 1 outcome 5 studies in 76 results : IBA
  3. Prealbumin (Transthyretin) : 1 outcome in 11 results : IBA
  4. Transforming Growth Factor beta (TGF-beta) : 1 outcome in 2 results : IBA
  5. Sirolimus (Rapamycin) : 1 outcome in 1 result : FDA 2
  6. Biological Markers (Surrogate Marker) : 5 studies in 5 results : IBA
  7. glucuronyl glucosamine glycan sulfate (Vessel) : 3 studies in 84 results : IBA
  8. Apolipoproteins : 3 studies in 54 results : IBA
  9. Cystatin C : 3 studies in 27 results : IBA
  10. Apolipoproteins E (ApoE) : 2 studies in 66 results : IBA
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Diseases Related to Cerebral Amyloid Angiopathy

  1. Alzheimer Disease (Alzheimer's Disease)
  2. Amyloid Plaque
  3. Hemorrhage
  4. Dementia (Dementias)
  5. Cerebral Hemorrhage
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Key Therapies for Cerebral Amyloid Angiopathy

Efficacy Chart >>
  1. Immunotherapy : 1 outcome in 9 results
  2. Liver Transplantation : 1 outcome in 1 result
  3. Neurosurgical Procedures : 1 study in 2 results
  4. Immunomodulation : 1 study in 1 result
  5. Transplants (Transplant) : 1 result
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