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Neurofibromatosis 2 (Neurofibromatosis Type II) Summary

Description: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.

Also Known As: Neurofibromatosis Type II; Bilateral Acoustic Neurofibromatosis; Neurofibromatosis Type 2; Neurofibromatosis II; 2 Neurofibromatosis, Type Show All >>

Networked: 502 relevant articles (7 outcomes, 36 trials/studies) for this Disease

Key Drugs and Agents for Neurofibromatosis 2

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. bevacizumab : 4 outcomes 1 study in 17 results : FDA 2
  2. Neurofibromin 2 (Merlin) : 2 outcomes 5 studies in 177 results : IBA
  3. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 2 outcomes in 3 results : IBA
  4. Schwannomatosis : 7 studies in 56 results : IBA
  5. DNA (Deoxyribonucleic Acid) : 2 studies in 18 results : IBA
  6. everolimus : 2 studies in 2 results : FDA 2
  7. Retinaldehyde (Retinal) : 1 study in 20 results : IBA
  8. Cyclin-Dependent Kinase Inhibitor p16 : 1 study in 5 results : IBA
  9. Genetic Markers (Genetic Marker) : 1 study in 4 results : IBA
  10. Paraffin : 1 study in 3 results : IBA
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Diseases Related to Neurofibromatosis 2

  1. Neoplasms (Cancer)
  2. Acoustic Neuroma (Acoustic Neurinoma)
  3. Deafness (Deaf Mutism)
  4. Neurilemmoma (Schwannoma)
  5. Meningioma (Meningiomas)
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Key Therapies for Neurofibromatosis 2

Efficacy Chart >>
  1. Auditory Brain Stem Implants (Auditory Brainstem Implants) : 1 outcome 4 studies in 51 results
  2. Radiotherapy : 1 outcome 1 study in 11 results
  3. Cochlear Implantation : 1 study in 15 results
  4. Heterologous Transplantation (Xenotransplantation) : 1 study in 2 results
  5. Cochlear Implants (Cochlear Implant) : 15 results
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