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Closed Head Injuries Summary

Description: Traumatic injuries to the cranium where the integrity of the skull is not compromised and no bone fragments or other objects penetrate the skull and dura mater. This frequently results in mechanical injury being transmitted to intracranial structures which may produce traumatic brain injuries, hemorrhage, or cranial nerve injury. (From Rowland, Merritt's Textbook of Neurology, 9th ed, p417)

Also Known As: Head Injuries, Closed; Head Injury, Blunt; Head Injury, Nonpenetrating; Injuries, Closed Head; Blunt Head Injuries Show All >>

Networked: 427 relevant articles (36 outcomes, 85 trials/studies) for this Disease

Key Drugs and Agents for Closed Head Injuries

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Hetastarch (Pentastarch) : 2 outcomes 2 studies in 2 results : FDA 5
  2. Cytidine Diphosphate Choline (Citicoline) : 2 outcomes 2 studies in 2 results : IBA
  3. Taurine : 2 outcomes 1 study in 2 results : FDA 2
  4. N-Methylaspartate (NMDA) : 2 outcomes in 7 results : IBA
  5. Acetylcholinesterase : 2 outcomes in 2 results : IBA
  6. Complement System Proteins (Complement) : 1 outcome 3 studies in 3 results : IBA
  7. Phenytoin (Dilantin) : 1 outcome 2 studies in 3 results : FDA 9 Generic
  8. N-Methyl-D-Aspartate Receptors (NMDA Receptors) : 1 outcome 1 study in 4 results : IBA
  9. Erythropoietin : 1 outcome 1 study in 4 results : FDA 1
  10. Isoflurane : 1 outcome 1 study in 3 results : FDA 7 Generic
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Diseases Related to Closed Head Injuries

  1. Brain Edema (Cerebral Edema)
  2. Memory Disorders (Memory Loss)
  3. Wounds and Injuries (Trauma)
  4. Hemorrhage
  5. Seizures (Seizure)
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Key Therapies for Closed Head Injuries

Efficacy Chart >>
  1. Critical Care : 1 outcome 2 studies in 6 results
  2. Hemodilution : 1 outcome 1 study in 1 result
  3. Tracheostomy : 1 outcome in 2 results
  4. Craniotomy : 2 studies in 9 results
  5. Decompressive Craniectomy : 1 study in 10 results
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