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HIV Protease Summary

Description: Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.

Also Known As: p16 pol gene product, HIV; p16 protease, HIV; HIV p16 protease; HTLV III Protease; Protease, HIV Show All >>

Networked: 238 relevant articles (13 outcomes, 18 trials/studies) for this Bio-Agent

Key Diseases for which HIV Protease is Relevant

  1. Acquired Immunodeficiency Syndrome (AIDS) : 5 outcomes 5 studies in 58 results
  2. HIV Infections (HIV Infection) : 5 outcomes 3 studies in 38 results
  3. Insulin Resistance : 1 outcome 1 study in 19 results
  4. Malaria : 1 outcome 1 study in 3 results
  5. Kidney Neoplasms (Kidney Cancer) : 1 outcome 1 study in 2 results
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Drugs Related to HIV Protease

  1. Ritonavir (Norvir)
  2. Nelfinavir (Viracept)
  3. RNA-Directed DNA Polymerase (Reverse Transcriptase)
  4. Histone Deacetylases (Histone Deacetylase)
  5. lopinavir (Kaletra)
  6. Protease Inhibitors (Protease Inhibitor)
  7. HIV Reverse Transcriptase
  8. Peptides
  9. Lipids
  10. Benzamides
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Therapies Related to HIV Protease

  1. Highly Active Antiretroviral Therapy (HAART)
  2. Drug Therapy (Chemotherapy)
  3. Lipectomy (Liposuction)
  4. Oral Administration
  5. Heterologous Transplantation (Xenotransplantation)
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