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Dizocilpine Maleate (Dizocilpine) Summary

Description: A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.

Also Known As: Dizocilpine; MK 801; MK-801; MK801; 5H-Dibenzo(a,d)cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S)-, (Z)-2-butenedioate (1:1)

Networked: 1755 relevant articles (139 outcomes, 205 trials/studies) for this Bio-Agent

Key Diseases for which Dizocilpine Maleate is Relevant

  1. Seizures (Seizure) : 37 outcomes 20 studies in 303 results
  2. Schizophrenia (Dementia Praecox) : 13 outcomes 41 studies in 200 results
  3. Ischemia : 13 outcomes 15 studies in 173 results
  4. Memory Disorders (Memory Loss) : 8 outcomes 5 studies in 50 results
  5. Brain Ischemia (Cerebral Ischemia) : 7 outcomes 10 studies in 64 results
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Drugs Related to Dizocilpine Maleate

  1. N-Methylaspartate (NMDA)
  2. Dizocilpine Maleate (Dizocilpine)
  3. Glutamic Acid (Glutamate)
  4. Ketamine
  5. N-Methyl-D-Aspartate Receptors (NMDA Receptors)
  6. Glycine (Aminoacetic Acid)
  7. Phencyclidine (Angel Dust)
  8. Scopolamine (Hyoscine)
  9. Clozapine (Clozaril)
  10. Magnesium
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Therapies Related to Dizocilpine Maleate

  1. Ligation
  2. Injections
  3. Spinal Injections
  4. Analgesia
  5. Intraperitoneal Injections
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