Search Login Register

Postpoliomyelitis Syndrome (Post-Polio Syndrome) Summary

Description: A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80)

Also Known As: Post-Polio Syndrome; Post-Poliomyelitis Muscular Atrophy; Muscular Atrophies, Post-Poliomyelitis; Muscular Atrophies, Postpoliomyelitis; Muscular Atrophy, Post-Poliomyelitis Show All >>

Networked: 73 relevant articles (3 outcomes, 15 trials/studies) for this Disease

Key Drugs and Agents for Postpoliomyelitis Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Intravenous Immunoglobulins (IVIG) : 1 outcome 1 study in 4 results : FDA 1
  2. Immunoglobulins (Immunoglobulin) : 3 studies in 6 results : IBA
  3. Antibodies : 2 studies in 6 results : IBA
  4. Immunoglobulin M (IgM) : 2 studies in 3 results : IBA
  5. Oligoclonal Bands : 1 study in 3 results : IBA
  6. Cytokines : 1 study in 3 results : IBA
  7. RNA (Ribonucleic Acid) : 1 study in 2 results : IBA
  8. Pyridostigmine Bromide (Pyridostigmine) : 1 study in 2 results : FDA 10 Generic
  9. Immunoglobulin G (IgG) : 1 study in 2 results : IBA
  10. coenzyme Q10 (CoQ10) : 1 study in 2 results : IBA
Show All >>

Diseases Related to Postpoliomyelitis Syndrome

  1. Fatigue
  2. Pain (Aches)
  3. Neurodegenerative Diseases (Neurodegenerative Disease)
  4. Sleep Disorders
  5. Fibrosis (Cirrhosis)
Show All >>

Key Therapies for Postpoliomyelitis Syndrome

Efficacy Chart >>
  1. Orthotic Devices (Orthosis) : 1 outcome 1 study in 3 results
  2. Self-Help Devices (Assistive Technology) : 1 outcome in 3 results
  3. Resistance Training : 1 study in 2 results
  4. Exercise Therapy (Therapy, Exercise) : 1 study in 1 result
  5. Denervation : 7 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.