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Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) Summary

Description: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Also Known As: Myalgic Encephalomyelitis; Encephalomyelitis, Myalgic; Postviral Fatigue Syndrome; Fatigue Syndrome, Chronic; Chronic Fatigue Disorder Show All >>

Networked: 866 relevant articles (41 outcomes, 139 trials/studies) for this Disease

Key Drugs and Agents for Chronic Fatigue Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antidepressive Agents (Antidepressants) : 3 outcomes 3 studies in 9 results : IBA
  2. Moclobemide (Arima) : 2 outcomes 3 studies in 3 results : IBA
  3. Melatonin : 2 outcomes 2 studies in 9 results : IBA
  4. epigallocatechin gallate (epigallocatechin-3-gallate) : 2 outcomes 1 study in 3 results : IBA
  5. Eicosapentaenoic Acid : 2 outcomes in 4 results : IBA
  6. Hydrocortisone (Cortisol) : 1 outcome 9 studies in 53 results : FDA 176 Generic
  7. Serotonin (5 Hydroxytryptamine) : 1 outcome 5 studies in 16 results : IBA
  8. APT : 1 outcome 5 studies in 5 results : IBA
  9. Fludrocortisone : 1 outcome 2 studies in 5 results : IBA
  10. Glutathione (Reduced Glutathione) : 1 outcome 2 studies in 3 results : IBA
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Diseases Related to Chronic Fatigue Syndrome

  1. Fatigue
  2. Fibromyalgia (Fibrositis)
  3. Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
  4. Infection
  5. Multiple Sclerosis
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Key Therapies for Chronic Fatigue Syndrome

Efficacy Chart >>
  1. Exercise Therapy (Therapy, Exercise) : 3 outcomes 9 studies in 23 results
  2. Aftercare (After-Treatment) : 2 outcomes 8 studies in 11 results
  3. Steam Bath (Sauna) : 1 outcome in 3 results
  4. Highly Active Antiretroviral Therapy (HAART) : 1 outcome in 1 result
  5. Acupuncture Therapy : 1 outcome in 1 result
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