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Rett Syndrome (Rett's Disorder) Summary

449 relevant articles (8 outcomes, 53 trials/studies) found for this Disease

Description: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)

Also Known As: Rett's Disorder; Syndrome, Rett; Rett's Syndrome; Autism Dementia Ataxia Loss of Purposeful Hand Use Syndrome; Cerebroatrophic Hyperammonemia Show All >>

Key Drugs and Agents for Rett Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. beta-Endorphin (Endorphin, beta) : 2 outcomes 1 study in 8 results : IBA
  2. Naltrexone (ReVia) : 2 outcomes 1 study in 3 results : FDA 6 Generic
  3. Methyl-CpG-Binding Protein 2 : 1 outcome 8 studies in 143 results : IBA
  4. Biogenic Amines (Biogenic Amine) : 1 outcome 4 studies in 14 results : IBA
  5. Carnitine (L-Carnitine) : 1 outcome 2 studies in 7 results : FDA 9 Generic
  6. Buspirone (Buspar) : 1 outcome 1 study in 2 results : FDA 15 Generic
  7. Brain-Derived Neurotrophic Factor (BDNF) : 1 outcome in 13 results : IBA
  8. Biotin (Vitamin H) : 1 outcome in 3 results : FDA 14
  9. Folic Acid (Vitamin M) : 1 outcome in 2 results : FDA 47 Generic
  10. Vitamins : 1 outcome in 1 result : IBA
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Diseases Related to Rett Syndrome

  1. Autistic Disorder (Autism)
  2. Syndrome
  3. Obesity
  4. Autonomic Nervous System Diseases (Dysautonomia)
  5. Atrophy
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Key Therapies for Rett Syndrome

Efficacy Chart >>
  1. Splints : 5 studies in 8 results
  2. Dilatation and Curettage (D&C) : 1 study in 1 result
  3. Music Therapy : 4 results
  4. Deep Sedation : 2 results
  5. Walking : 2 results
Show All >>

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