Search Login Register

Zellweger Syndrome (Zellweger's Syndrome) Summary

Description: An autosomal recessive disorder due to defects in PEROXISOME biogenesis which involves more than 13 genes encoding peroxin proteins of the peroxisomal membrane and matrix. Zellweger syndrome is typically seen in the neonatal period with features such as dysmorphic skull; MUSCLE HYPOTONIA; SENSORINEURAL HEARING LOSS; visual compromise; SEIZURES; progressive degeneration of the KIDNEYS and the LIVER. Zellweger-like syndrome refers to phenotypes resembling the neonatal Zellweger syndrome but seen in children or adults with apparently intact peroxisome biogenesis.

Also Known As: Zellweger's Syndrome; Cerebro-Hepato-Renal Syndrome; Zellweger Disease; Cerebro Hepato Renal Syndrome; Cerebro-Hepato-Renal Syndromes Show All >>

Networked: 415 relevant articles (4 outcomes, 27 trials/studies) for this Disease

Key Drugs and Agents for Zellweger Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Acids : 2 outcomes in 18 results : IBA
  2. Bile Acids and Salts (Bile Acids) : 1 outcome 4 studies in 18 results : IBA
  3. Fatty Acids (Saturated Fatty Acids) : 1 outcome 2 studies in 60 results : IBA
  4. pipecolic acid : 1 outcome 1 study in 17 results : IBA
  5. Ethyl Ether (Ether) : 1 outcome 1 study in 13 results : IBA
  6. Phytanic Acid : 1 outcome in 23 results : IBA
  7. Acetyl-CoA C-Acyltransferase (beta Ketothiolase) : 1 outcome in 4 results : IBA
  8. Palmitic Acid (Hexadecanoic Acid) : 1 outcome in 1 result : IBA
  9. Carbon Dioxide : 1 outcome in 1 result : IBA
  10. Proteins (Proteins, Gene) : 2 studies in 31 results : IBA
Show All >>

Diseases Related to Zellweger Syndrome

  1. Liver Diseases (Liver Disease)
  2. Refsum Disease (Refsum's Disease)
  3. Peroxisomal Disorders (Peroxisomal Disorder)
  4. Cerebrotendinous Xanthomatosis
  5. Hyperoxaluria
Show All >>

Key Therapies for Zellweger Syndrome

Efficacy Chart >>
  1. Nursing Care : 1 study in 2 results
  2. Lasers (Laser) : 1 study in 1 result
  3. Transplantation (Transplant Recipients) : 1 result
  4. Sutures (Suture) : 1 result
  5. Anesthesia : 1 result

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.