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Wallerian Degeneration Summary

Description: Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.

Also Known As: Degeneration, Wallerian

Networked: 548 relevant articles (14 outcomes, 57 trials/studies) for this Disease

Key Drugs and Agents for Wallerian Degeneration

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Messenger RNA (mRNA) : 1 outcome 2 studies in 26 results : IBA
  2. Sodium Channels (Sodium Channel) : 1 outcome 2 studies in 4 results : IBA
  3. Proteasome Endopeptidase Complex (Proteasome) : 1 outcome 1 study in 8 results : IBA
  4. Substance P : 1 outcome 1 study in 3 results : IBA
  5. Calcitonin Gene-Related Peptide : 1 outcome 1 study in 1 result : IBA
  6. Somatostatin (Somatotropin Release-Inhibiting Factor) : 1 outcome 1 study in 1 result : IBA
  7. Nerve Growth Factors (Neurotrophins) : 1 outcome in 7 results : IBA
  8. Vincristine (Oncovin) : 1 outcome in 4 results : FDA 17 Generic
  9. RNA (Ribonucleic Acid) : 1 outcome in 3 results : IBA
  10. Caspase 3 (Caspase-3) : 1 outcome in 2 results : IBA
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Diseases Related to Wallerian Degeneration

  1. Hyperalgesia
  2. Muscular Atrophy (Muscle Atrophy)
  3. Demyelinating Diseases (Demyelinating Disease)
  4. Nerve Degeneration
  5. Neuralgia (Stump Neuralgia)
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Key Therapies for Wallerian Degeneration

Efficacy Chart >>
  1. Axotomy : 1 outcome 2 studies in 39 results
  2. Nerve Crush : 1 outcome 2 studies in 10 results
  3. Transplants (Transplant) : 1 outcome in 17 results
  4. Intraperitoneal Injections : 1 outcome in 2 results
  5. Ganglionectomy : 1 study in 8 results
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