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Tuftsin Summary

Description: N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.

Also Known As: L-Thr-L-Lys-L-Pro-L-Arg; L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine; Taftsin; L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-

Networked: 121 relevant articles (23 outcomes, 15 trials/studies) for this Bio-Agent

Key Diseases for which Tuftsin is Relevant

  1. Infection : 8 outcomes 7 studies in 28 results
  2. Candidiasis (Moniliasis) : 5 outcomes 2 studies in 5 results
  3. Neoplasms (Cancer) : 3 outcomes 1 study in 21 results
  4. Cryptococcosis : 2 outcomes 1 study in 2 results
  5. Visceral Leishmaniasis (Kala Azar) : 2 outcomes in 2 results
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Drugs Related to Tuftsin

  1. Liposomes (Liposome)
  2. Amphotericin B (Amphotericin)
  3. Adenosine Monophosphate (AMP)
  4. Etoposide (VP 16)
  5. Diethylcarbamazine (Hetrazan)
  6. Carbon Monoxide
  7. Staphylococcal Protein A (A, Protein)
  8. Nystatin (Mycostatin)
  9. bestatin (ubenimex)
  10. Opioid Peptides (Opioid Peptide)
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Therapies Related to Tuftsin

  1. Immunotherapy
  2. Drug Therapy (Chemotherapy)
  3. Intraperitoneal Injections
  4. Splenectomy
  5. Injections
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