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Chagas Disease (American Trypanosomiasis) Summary

1784 relevant articles (74 outcomes, 159 trials/studies) found for this Disease

Description: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.

Also Known As: American Trypanosomiasis; South American Trypanosomiasis; Chagas' Disease; Disease, Chagas; Disease, Chagas' Show All >>

Key Drugs and Agents for Chagas Disease

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. benzonidazole (benznidazole) : 12 outcomes 9 studies in 99 results : IBA
  2. Antigens : 9 outcomes 18 studies in 237 results : IBA
  3. Nifurtimox : 8 outcomes 8 studies in 62 results : IBA
  4. Allopurinol (Remid) : 6 outcomes 2 studies in 20 results : FDA 25 Generic
  5. Antibodies : 5 outcomes 11 studies in 182 results : IBA
  6. Complement System Proteins (Complement) : 3 outcomes 6 studies in 80 results : IBA
  7. Ketoconazole (Nizoral) : 3 outcomes 2 studies in 12 results : FDA 20 Generic
  8. Insecticides : 3 outcomes 1 study in 27 results : IBA
  9. Gentian Violet (Violet, Crystal) : 3 outcomes 1 study in 20 results : FDA 2
  10. Itraconazole (Sporanox) : 2 outcomes 3 studies in 10 results : FDA 4 Generic
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Diseases Related to Chagas Disease

  1. Infection
  2. Leishmaniasis
  3. Malaria
  4. Onchocerciasis
  5. Cutaneous Leishmaniasis
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Key Therapies for Chagas Disease

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 3 outcomes 14 studies in 107 results
  2. Heart Transplantation (Grafting, Heart) : 2 outcomes 2 studies in 28 results
  3. Blood Transfusion (Blood Transfusions) : 1 outcome 4 studies in 68 results
  4. Transplants (Transplant) : 1 outcome 1 study in 22 results
  5. Chemoprevention : 1 outcome 1 study in 7 results
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