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African Trypanosomiasis (Nagana) Summary

459 relevant articles (14 outcomes, 33 trials/studies) found for this Disease

Description: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the tsetse fly. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Also Known As: Nagana; Trypanosomiasis, African; African Trypanosomiases; Sleeping Sickness, African; Trypanosomiases, African Show All >>

Key Drugs and Agents for African Trypanosomiasis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Eflornithine (Ornidyl) : 4 outcomes 4 studies in 32 results : FDA 2
  2. Pentamidine (NebuPent) : 3 outcomes 1 study in 21 results : FDA 6 Generic
  3. Suramin (Suramin Sodium) : 2 outcomes 2 studies in 23 results : IBA
  4. furamidine (DB75) : 2 outcomes 2 studies in 6 results : IBA
  5. Melarsoprol (Mel B) : 2 outcomes 1 study in 38 results : IBA
  6. Ornithine Decarboxylase (Decarboxylase, Ornithine) : 1 outcome 1 study in 8 results : IBA
  7. Membrane Glycoproteins (Membrane Glycoprotein) : 1 outcome 1 study in 8 results : IBA
  8. Ornithine : 1 outcome 1 study in 3 results : IBA
  9. pafuramidine : 1 outcome 1 study in 2 results : IBA
  10. Trypanocidal Agents : 1 outcome in 5 results : IBA
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Diseases Related to African Trypanosomiasis

  1. Leishmaniasis
  2. Chagas Disease (American Trypanosomiasis)
  3. Malaria
  4. Trypanosomiasis
  5. Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
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Key Therapies for African Trypanosomiasis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 studies in 49 results
  2. Aftercare (After-Treatment) : 1 study in 8 results
  3. Therapeutics : 1 study in 2 results
  4. Chemoprevention : 6 results
  5. Investigational Therapies (Experimental Therapy) : 2 results
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