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Trimethoprim (Proloprim) Summary

Description: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.

Also Known As: Proloprim; Trimpex; 2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)methyl)-

Networked: 1631 relevant articles (161 outcomes, 163 trials/studies) for this Drug

Key Diseases for which Trimethoprim is Relevant

  1. Infection : 37 outcomes 31 studies in 335 results
  2. Urinary Tract Infections (Urinary Tract Infection) : 29 outcomes 32 studies in 254 results
  3. Pneumonia (Pneumonitis) : 11 outcomes 5 studies in 58 results
  4. Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) : 8 outcomes 3 studies in 77 results
  5. Typhoid Fever (Typhoid) : 7 outcomes in 50 results
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Drugs Related to Trimethoprim

  1. Sulfamethoxazole
  2. Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
  3. Ampicillin (Omnipen)
  4. Thymidine Monophosphate (TMP)
  5. Sulfadiazine (Sulphadiazine)
  6. Rifampin (Rifampicin)
  7. Dapsone
  8. Ciprofloxacin (Cipro)
  9. Chloramphenicol (Chloromycetin)
  10. Tetracycline (Achromycin)
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Therapies Related to Trimethoprim

  1. Drug Therapy (Chemotherapy)
  2. Aftercare (After-Treatment)
  3. Chemoprevention
  4. Oral Administration
  5. Prostatectomy (Retropubic Prostatectomy)
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