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Trigeminal Neuralgia (Tic Douloureux) Summary

Description: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the trigeminal nerve. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)

Also Known As: Tic Douloureux; Epileptiform Neuralgia; Fothergill Disease; Secondary Trigeminal Neuralgia; Trifacial Neuralgia Show All >>

Networked: 1689 relevant articles (168 outcomes, 178 trials/studies) for this Disease

Key Drugs and Agents for Trigeminal Neuralgia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Carbamazepine (Tegretol) : 31 outcomes 22 studies in 210 results : FDA 24 Generic
  2. Anticonvulsants (Antiepileptic Drugs) : 14 outcomes 9 studies in 45 results : IBA
  3. Baclofen : 10 outcomes 2 studies in 27 results : FDA 31 Generic
  4. lamotrigine (Lamictal) : 8 outcomes 6 studies in 23 results : FDA 33 Generic
  5. Glycerol (Glycerine) : 6 outcomes 8 studies in 107 results : FDA 6 Generic
  6. gabapentin (Neurontin) : 6 outcomes 4 studies in 26 results : FDA 37 Generic
  7. Phenytoin (Dilantin) : 6 outcomes 2 studies in 31 results : FDA 9 Generic
  8. oxcarbazepine (Trileptal) : 5 outcomes 4 studies in 22 results : FDA 12 Generic
  9. Type A Botulinum Toxins (Botulinum A Toxin) : 2 outcomes 8 studies in 17 results : FDA 2
  10. Lidocaine (Xylocaine) : 2 outcomes 5 studies in 24 results : FDA 168 Generic
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Diseases Related to Trigeminal Neuralgia

  1. Pain (Aches)
  2. Hemifacial Spasm
  3. Neuralgia (Stump Neuralgia)
  4. Postherpetic Neuralgia
  5. Migraine Disorders (Migraine)
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Key Therapies for Trigeminal Neuralgia

Efficacy Chart >>
  1. Decompression : 42 outcomes 40 studies in 518 results
  2. Rhizotomy : 13 outcomes 12 studies in 140 results
  3. Electrocoagulation (Electrocautery) : 7 outcomes 8 studies in 132 results
  4. Drug Therapy (Chemotherapy) : 5 outcomes 3 studies in 34 results
  5. Particle Accelerators : 4 outcomes 3 studies in 12 results
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