Search Login Register

Androgen-Insensitivity Syndrome (Testicular Feminization) Summary

542 relevant articles (5 outcomes, 51 trials/studies) found for this Disease

Description: A familial form of PSEUDOHERMAPHRODITISM transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY.

Also Known As: Testicular Feminization; Reifenstein Syndrome; Reifenstein's Syndrome; Androgen-Insensitivity Syndrome, Complete; Androgen-Insensitivity Syndrome, Partial Show All >>

Key Drugs and Agents for Androgen-Insensitivity Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Testosterone (Sustanon) : 2 outcomes 4 studies in 62 results : FDA 12 Generic
  2. Dihydrotestosterone (Androstanolone) : 2 outcomes 4 studies in 31 results : IBA
  3. Hormones : 1 outcome 4 studies in 31 results : IBA
  4. Steroids : 1 outcome in 13 results : IBA
  5. Cholestenone 5 alpha-Reductase (5 alpha-Reductase) : 1 outcome in 12 results : IBA
  6. Nitrogen : 1 outcome in 3 results : IBA
  7. Androstenedione (4 Androstene 3,17 dione) : 1 outcome in 2 results : IBA
  8. Esters : 1 outcome in 1 result : IBA
  9. Androgen Receptors (Androgen Receptor) : 21 studies in 268 results : IBA
  10. Androgens : 6 studies in 38 results : IBA
Show All >>

Diseases Related to Androgen-Insensitivity Syndrome

  1. Syndrome
  2. Gonadal Dysgenesis (Gonadal Agenesis)
  3. Virilism (Virilization)
  4. Hyperthyroidism
  5. Pseudohermaphroditism
Show All >>

Key Therapies for Androgen-Insensitivity Syndrome

Efficacy Chart >>
  1. Laparotomy : 1 outcome in 3 results
  2. Contraception (Birth Control) : 1 study in 1 result
  3. Orchiectomy (Orchidectomy) : 11 results
  4. Castration : 6 results
  5. Transplants (Transplant) : 2 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2008 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.