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Tay-Sachs Disease Summary

348 relevant articles (1 outcomes, 24 trials/studies) found for this Disease

Description: An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, dementia, and blindness. It is caused by mutation in the alpha subunit of the HEXOSAMINIDASE A resulting in lipid-laden ganglion cells. It is also known as the B variant (with increased HEXOSAMINIDASE B but absence of hexosaminidase A) and is strongly associated with Ashkenazic Jewish ancestry.

Also Known As: Amaurotic Familial Idiocy; Deficiency Disease Hexosaminidase A; Familial Amaurotic Idiocy; GM2 Gangliosidosis, B Variant; GM2 Gangliosidosis, Type I Show All >>

Key Drugs and Agents for Tay-Sachs Disease

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. beta-N-Acetylhexosaminidases : 1 outcome 3 studies in 96 results : IBA
  2. Lipids : 6 studies in 10 results : IBA
  3. Hexosaminidase A (Hex A) : 5 studies in 128 results : IBA
  4. Hexosaminidases (Hexosaminidase) : 3 studies in 41 results : IBA
  5. G(M2) Ganglioside (Ganglioside GM2) : 1 study in 25 results : IBA
  6. Enzymes : 1 study in 9 results : IBA
  7. RNA (Ribonucleic Acid) : 1 study in 3 results : IBA
  8. Proteins (Proteins, Gene) : 1 study in 2 results : IBA
  9. Synucleins : 1 study in 1 result : IBA
  10. Fluorescein (Funduscein) : 1 study in 1 result : FDA 2
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Diseases Related to Tay-Sachs Disease

  1. Gangliosidoses (Gangliosidosis)
  2. Lipidoses
  3. Sandhoff Disease (Sandhoff's Disease)
  4. GM2 Gangliosidoses (GM2 Gangliosidosis)
  5. Gaucher Disease (Gaucher's Disease)
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Key Therapies for Tay-Sachs Disease

Efficacy Chart >>
  1. Transplants (Transplant) : 1 result
  2. Tissue Transplantation : 1 result
  3. Plasmapheresis : 1 result
  4. Lasers (Laser) : 1 result
  5. Contraception (Birth Control) : 1 result
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