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Substance P Summary

Description: An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.

Also Known As: Euler-Gaddum Substance P; Hypothalamic Substance P; SP(1-11); Euler Gaddum Substance P; P, Euler-Gaddum Substance Show All >>

Networked: 3783 relevant articles (65 outcomes, 457 trials/studies) for this Bio-Agent

Key Diseases for which Substance P is Relevant

  1. Pain (Aches) : 13 outcomes 52 studies in 593 results
  2. Edema : 9 outcomes 6 studies in 79 results
  3. Neurogenic Inflammation : 4 outcomes 24 studies in 270 results
  4. Hyperalgesia : 3 outcomes 16 studies in 170 results
  5. Inflammation : 2 outcomes 39 studies in 416 results
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Drugs Related to Substance P

  1. Neuropeptides
  2. Calcitonin Gene-Related Peptide
  3. Capsaicin (Zostrix)
  4. Bradykinin
  5. Diphenhydramine (Benadryl)
  6. Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
  7. Methysergide (Sansert)
  8. Somatostatin (Somatotropin Release-Inhibiting Factor)
  9. Octreotide (Sandostatin)
  10. Neurokinin A
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Therapies Related to Substance P

  1. Denervation
  2. Acupuncture Points (Acupuncture Point)
  3. Axotomy
  4. Intravenous Injections
  5. Catgut
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