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Status Epilepticus (Complex Partial Status Epilepticus) Summary

Description: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Also Known As: Complex Partial Status Epilepticus; Grand Mal Status Epilepticus; Status Epilepticus, Complex Partial; Petit Mal Status; Status Epilepticus, Electrographic Show All >>

Networked: 4032 relevant articles (246 outcomes, 487 trials/studies) for this Disease

Key Drugs and Agents for Status Epilepticus

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Midazolam (Versed) : 25 outcomes 22 studies in 139 results : FDA 31 Generic
  2. Diazepam (Valium) : 24 outcomes 24 studies in 254 results : FDA 84 Generic
  3. Valproic Acid (Valproate, Semisodium) : 24 outcomes 18 studies in 150 results : FDA 51 Generic
  4. Pilocarpine (Ocusert) : 22 outcomes 141 studies in 817 results : FDA 10 Generic
  5. etiracetam (levetiracetam) : 22 outcomes 19 studies in 92 results : FDA 45 Generic
  6. Phenytoin (Dilantin) : 22 outcomes 14 studies in 202 results : FDA 9 Generic
  7. Anticonvulsants (Antiepileptic Drugs) : 15 outcomes 14 studies in 193 results : IBA
  8. Benzodiazepines : 15 outcomes 14 studies in 172 results : IBA
  9. Kainic Acid (Kainate) : 10 outcomes 64 studies in 460 results : IBA
  10. Lithium : 10 outcomes 40 studies in 201 results : IBA
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Diseases Related to Status Epilepticus

  1. Seizures (Seizure)
  2. Status Epilepticus (Complex Partial Status Epilepticus)
  3. Epilepsy (Aura)
  4. Encephalitis (Encephalitis, Rasmussen)
  5. Stroke (Strokes)
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Key Therapies for Status Epilepticus

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 outcomes 4 studies in 37 results
  2. Injections : 4 outcomes 1 study in 38 results
  3. Ketogenic Diet : 4 outcomes 1 study in 31 results
  4. Anesthesia : 2 outcomes 1 study in 35 results
  5. Intravenous Infusions : 2 outcomes in 19 results
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