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Spectrin Summary

Description: A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.

Also Known As: alpha-Spectrin; beta-Spectrin; alpha Spectrin; beta Spectrin; Spectrins

Networked: 644 relevant articles (6 outcomes, 44 trials/studies) for this Bio-Agent

Key Diseases for which Spectrin is Relevant

  1. Brain Injuries (Brain Injury) : 1 outcome 4 studies in 32 results
  2. Hemolysis : 1 outcome 2 studies in 23 results
  3. Malaria : 1 outcome 2 studies in 9 results
  4. Seizures (Seizure) : 1 outcome 2 studies in 6 results
  5. Proteinuria : 1 outcome in 1 result
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Drugs Related to Spectrin

  1. Calpain
  2. Caspase 3 (Caspase-3)
  3. 3,6-dimethylaminodibenzopyriodonium citrate
  4. calpain inhibitors
  5. Lipid Bilayers (Lipid Bilayer)
  6. ((1S)- 1- ((((1S)- 1- benzyl- 3- cyclopropylamino- 2,3- di- oxopropyl)amino)carbonyl)- 3- methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester
  7. NF-kappa B (NF-kB)
  8. Spectrin
  9. Proteins (Proteins, Gene)
  10. N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))
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Therapies Related to Spectrin

  1. Splenectomy
  2. Surgical Instruments (Clip)
  3. Aftercare (After-Treatment)
  4. Ligation
  5. Perioperative Period
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