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Sjogren's Syndrome (Sjogren Syndrome) Summary

Description: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Also Known As: Sjogren Syndrome; Syndrome, Sicca; Sjogrens Syndrome; Syndrome, Sjogren's; Sicca Syndrome

Networked: 858 relevant articles (26 outcomes, 64 trials/studies) for this Disease

Key Drugs and Agents for Sjogren's Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. rituximab (Mabthera) : 4 outcomes 3 studies in 20 results : FDA 3
  2. Immunoglobulin A (IgA) : 2 outcomes 3 studies in 20 results : IBA
  3. SS-B antibodies : 2 outcomes 1 study in 10 results : IBA
  4. cevimeline (Evoxac) : 2 outcomes 1 study in 4 results : FDA 1
  5. Cholesterol : 2 outcomes 1 study in 2 results : IBA
  6. Autoantibodies : 1 outcome 4 studies in 78 results : IBA
  7. Proteins (Proteins, Gene) : 1 outcome 2 studies in 13 results : IBA
  8. Immunoglobulin G (IgG) : 1 outcome 1 study in 38 results : IBA
  9. Immunoglobulin M (IgM) : 1 outcome 1 study in 18 results : IBA
  10. Rheumatoid Factor : 1 outcome 1 study in 17 results : IBA
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Diseases Related to Sjogren's Syndrome

  1. Xerostomia
  2. Xerophthalmia
  3. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  4. Inflammation
  5. Infection
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Key Therapies for Sjogren's Syndrome

Efficacy Chart >>
  1. Immunotherapy : 1 outcome 1 study in 1 result
  2. Aftercare (After-Treatment) : 1 outcome in 2 results
  3. Retreatment : 1 outcome in 1 result
  4. Oral Hygiene (Dental Hygiene) : 1 study in 4 results
  5. Lasers (Laser) : 1 study in 2 results
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