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Serum Sickness Summary

Description: Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.

Also Known As: Serum Sicknesses; Sickness, Serum; Sicknesses, Serum

Networked: 526 relevant articles (12 outcomes, 40 trials/studies) for this Disease

Key Drugs and Agents for Serum Sickness

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antigen-Antibody Complex (Immune Complex) : 3 outcomes 7 studies in 113 results : IBA
  2. rituximab (Mabthera) : 2 outcomes in 19 results : FDA 3
  3. Penicillins (Penicillin) : 1 outcome 1 study in 26 results : FDA 1
  4. Antilymphocyte Serum (Anti-Thymocyte Globulin) : 1 outcome 1 study in 15 results : IBA
  5. Complement System Proteins (Complement) : 1 outcome in 19 results : IBA
  6. Steroids : 1 outcome in 6 results : IBA
  7. Methylprednisolone : 1 outcome in 3 results : FDA 18 Generic
  8. Inosine Triphosphate (ITP) : 1 outcome in 2 results : IBA
  9. gamma-Globulins (gamma-Globulin) : 1 outcome in 2 results : IBA
  10. DNA Vaccines : 1 outcome in 1 result : IBA
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Diseases Related to Serum Sickness

  1. Fever (Fevers)
  2. Arthralgia (Joint Pain)
  3. Hypergammaglobulinemia (Hyperimmunoglobulinemia)
  4. Aplastic Anemia (Anemia, Hypoplastic)
  5. Interstitial Lung Diseases (Interstitial Lung Disease)
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Key Therapies for Serum Sickness

Efficacy Chart >>
  1. Homologous Transplantation (Allograft) : 1 outcome 1 study in 3 results
  2. Transplants (Transplant) : 1 outcome in 6 results
  3. Injections : 1 study in 13 results
  4. Immunotherapy : 1 study in 6 results
  5. Transplantation (Transplant Recipients) : 6 results
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