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Sciatica (Sciatic Neuralgia) Summary

Description: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.

Also Known As: Sciatic Neuralgia; Sciatica, Bilateral; Bilateral Sciatica; Bilateral Sciaticas; Neuralgias, Sciatic Show All >>

Networked: 745 relevant articles (85 outcomes, 126 trials/studies) for this Disease

Key Drugs and Agents for Sciatica

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 7 outcomes 12 studies in 26 results : IBA
  2. Chymopapain (Chymodiactin) : 4 outcomes 9 studies in 27 results : FDA 2
  3. TNFR-Fc fusion protein (etanercept) : 4 outcomes 4 studies in 8 results : FDA 2
  4. Adrenal Cortex Hormones (Corticosteroids) : 3 outcomes 4 studies in 23 results : IBA
  5. Steroids : 3 outcomes 4 studies in 22 results : IBA
  6. Non-Steroidal Anti-Inflammatory Agents (NSAIDs) : 3 outcomes 3 studies in 11 results : IBA
  7. meloxicam (Mobic) : 3 outcomes 2 studies in 5 results : FDA 24 Generic
  8. infliximab (Remicade) : 2 outcomes 6 studies in 7 results : FDA 2
  9. Methylprednisolone : 2 outcomes 2 studies in 8 results : FDA 18 Generic
  10. Lidocaine (Xylocaine) : 2 outcomes 2 studies in 8 results : FDA 168 Generic
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Diseases Related to Sciatica

  1. Low Back Pain (Lumbago)
  2. Pain (Aches)
  3. Prolapse
  4. Back Pain (Backache)
  5. Radiculopathy (Radiculopathy, Cervical)
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Key Therapies for Sciatica

Efficacy Chart >>
  1. Injections : 9 outcomes 15 studies in 60 results
  2. Diskectomy (Discectomy) : 7 outcomes 6 studies in 70 results
  3. Intervertebral Disk Chemolysis (Discolysis) : 7 outcomes 1 study in 53 results
  4. Epidural Injections : 5 outcomes 9 studies in 42 results
  5. Traction : 2 outcomes 7 studies in 33 results
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