Search Login Register

Retrograde Degeneration Summary

Description: Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.

Also Known As: Axonal Reaction; Trans-Synaptic Degeneration; Axon Reactions; Axonal Reactions; Degeneration, Nissl Show All >>

Networked: 209 relevant articles (4 outcomes, 19 trials/studies) for this Disease

Key Drugs and Agents for Retrograde Degeneration

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Dopamine (Intropin) : 1 outcome in 6 results : FDA 36 Generic
  2. Messenger RNA (mRNA) : 1 outcome in 2 results : IBA
  3. Colchicine : 1 outcome in 1 result : FDA 13 Generic
  4. Immunotoxins (Immunotoxin) : 1 outcome in 1 result : IBA
  5. Eflornithine (Ornidyl) : 1 outcome in 1 result : FDA 2
  6. Retinaldehyde (Retinal) : 1 study in 24 results : IBA
  7. Horseradish Peroxidase : 1 study in 7 results : IBA
  8. Silver : 1 study in 4 results : IBA
  9. 1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP) : 1 study in 3 results : IBA
  10. Oxygen : 1 study in 3 results : IBA
Show All >>

Diseases Related to Retrograde Degeneration

  1. Wounds and Injuries (Trauma)
  2. Multiple Sclerosis
  3. Viral Encephalitis
  4. Ganglion Cysts (Ganglion)
  5. Atrophy
Show All >>

Key Therapies for Retrograde Degeneration

Efficacy Chart >>
  1. Ganglionectomy : 1 outcome in 1 result
  2. Axotomy : 4 studies in 28 results
  3. Injections : 2 studies in 7 results
  4. Transplants (Transplant) : 1 study in 6 results
  5. Traction : 1 study in 3 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.