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Retinal Degeneration Summary

Description: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Also Known As: Degeneration, Retinal; Degenerations, Retinal; Retinal Degenerations

Networked: 2246 relevant articles (89 outcomes, 261 trials/studies) for this Disease

Key Drugs and Agents for Retinal Degeneration

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Retinaldehyde (Retinal) : 18 outcomes 76 studies in 648 results : IBA
  2. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) : 6 outcomes 5 studies in 15 results : IBA
  3. Rhodopsin (Visual Purple) : 4 outcomes 14 studies in 175 results : IBA
  4. Sodium Glutamate (Accent) : 3 outcomes 8 studies in 15 results : IBA
  5. Ciliary Neurotrophic Factor (CNTF) : 3 outcomes 3 studies in 26 results : IBA
  6. Vitamin A (Retinol) : 3 outcomes 3 studies in 25 results : FDA 33 Generic
  7. calpain inhibitors : 3 outcomes 1 study in 8 results : IBA
  8. Kainic Acid (Kainate) : 3 outcomes 1 study in 5 results : IBA
  9. Iron : 2 outcomes 4 studies in 45 results : IBA
  10. Brain-Derived Neurotrophic Factor (BDNF) : 2 outcomes 4 studies in 12 results : IBA
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Diseases Related to Retinal Degeneration

  1. Retinitis Pigmentosa (Pigmentary Retinopathy)
  2. Retinal Degeneration
  3. Ischemia
  4. Diabetic Retinopathy (Retinopathy, Diabetic)
  5. Hemorrhage
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Key Therapies for Retinal Degeneration

Efficacy Chart >>
  1. Transplantation (Transplant Recipients) : 7 outcomes 13 studies in 76 results
  2. Cell Transplantation : 2 outcomes 2 studies in 7 results
  3. Intravitreal Injections : 1 outcome 1 study in 23 results
  4. Visual Prosthesis : 1 outcome 1 study in 10 results
  5. Microspheres (Microsphere) : 1 outcome 1 study in 5 results
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