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Renin Summary

Description: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

Also Known As: Big Renin; Cryorenin; Inactive Renin; Pre-Prorenin; Preprorenin Show All >>

Networked: 9108 relevant articles (270 outcomes, 881 trials/studies) for this Bio-Agent

Key Diseases for which Renin is Relevant

  1. Hypertension (High Blood Pressure) : 122 outcomes 405 studies in 4212 results
  2. Heart Failure : 26 outcomes 54 studies in 444 results
  3. Renal Artery Obstruction (Renal Artery Stenosis) : 14 outcomes 28 studies in 230 results
  4. Hyperaldosteronism (Conn Syndrome) : 11 outcomes 37 studies in 538 results
  5. Body Weight (Weight, Body) : 8 outcomes 20 studies in 259 results
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Drugs Related to Renin

  1. Aldosterone
  2. Angiotensins
  3. Captopril (Capoten)
  4. Sodium
  5. Norepinephrine (Noradrenaline)
  6. Angiotensin II
  7. aliskiren
  8. Spironolactone (Aldactone)
  9. Calcium
  10. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
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Therapies Related to Renin

  1. Nephrectomy
  2. Adrenalectomy
  3. Transplants (Transplant)
  4. Drug Therapy (Chemotherapy)
  5. Transplantation (Transplant Recipients)
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