Search Login Register

Transglutaminases Summary

Description: Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.

Also Known As: Gamma-Glutamyltransferases, Glutaminyl-Peptide; Glutaminyl Peptide Gamma Glutamyltransferases; Protein Glutamine gamma Glutamyltransferases; gamma-Glutamyltransferases, Protein-Glutamine; Glutaminyl-Peptide Gamma-Glutamyltransferases Show All >>

Networked: 76 relevant articles (0 outcomes, 3 trials/studies) for this Bio-Agent

Key Diseases for which Transglutaminases is Relevant

  1. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 study in 13 results
  2. Celiac Disease (Celiac Sprue) : 1 study in 8 results
  3. Huntington Disease (Huntington's Disease) : 1 study in 3 results
  4. Crohn Disease (Crohn's Disease) : 1 study in 1 result
  5. Neoplasms (Cancer) : 8 results
Show All >>

Drugs Related to Transglutaminases

  1. Antibodies
  2. Neuropeptides
  3. Histones (Histone)
  4. DNA (Deoxyribonucleic Acid)
  5. Chromatin
  6. polyglutamine
  7. Enzymes
  8. Proteins (Proteins, Gene)
  9. Calcium
  10. Autoantibodies
Show All >>

Therapies Related to Transglutaminases

  1. Laser In Situ Keratomileusis (LASIK)

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.