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Polyneuropathies (Polyneuropathy) Summary

Description: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

Also Known As: Polyneuropathy; Polyneuropathy, Critical Illness; Polyneuropathy, Familial; Polyneuropathy, Inherited; Polyneuropathy, Motor Show All >>

Networked: 3436 relevant articles (184 outcomes, 312 trials/studies) for this Disease

Key Drugs and Agents for Polyneuropathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Intravenous Immunoglobulins (IVIG) : 25 outcomes 23 studies in 124 results : FDA 1
  2. Immunoglobulins (Immunoglobulin) : 17 outcomes 17 studies in 134 results : IBA
  3. Adrenal Cortex Hormones (Corticosteroids) : 13 outcomes 3 studies in 46 results : IBA
  4. Immunoglobulin M (IgM) : 8 outcomes 30 studies in 244 results : IBA
  5. Prednisone (Sone) : 7 outcomes 1 study in 26 results : FDA 119 Generic
  6. Immunoglobulin G (IgG) : 6 outcomes 4 studies in 98 results : IBA
  7. rituximab (Mabthera) : 4 outcomes 8 studies in 34 results : FDA 3
  8. Lidocaine (Xylocaine) : 4 outcomes 2 studies in 7 results : FDA 168 Generic
  9. Melphalan (Alkeran) : 4 outcomes in 8 results : FDA 2 Generic
  10. Prealbumin (Transthyretin) : 3 outcomes 25 studies in 396 results : IBA
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Diseases Related to Polyneuropathies

  1. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
  2. Myasthenia Gravis
  3. Dermatomyositis (Dermatopolymyositis)
  4. Pain (Aches)
  5. Paraproteinemias (Monoclonal Gammopathy)
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Key Therapies for Polyneuropathies

Efficacy Chart >>
  1. Plasmapheresis : 9 outcomes 5 studies in 54 results
  2. Drug Therapy (Chemotherapy) : 7 outcomes 4 studies in 52 results
  3. Liver Transplantation : 5 outcomes 9 studies in 121 results
  4. Plasma Exchange : 5 outcomes 6 studies in 57 results
  5. Transplants (Transplant) : 5 outcomes 3 studies in 48 results
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