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Paraproteinemias (Monoclonal Gammopathy) Summary

Description: A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.

Also Known As: Monoclonal Gammopathy; Paraproteinemia; Monoclonal Gammapathies; Cell Dyscrasia, Plasma; Cell Dyscrasias, Plasma Show All >>

Networked: 2176 relevant articles (47 outcomes, 118 trials/studies) for this Disease

Key Drugs and Agents for Paraproteinemias

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Immunoglobulin A (IgA) : 6 outcomes 8 studies in 232 results : IBA
  2. Melphalan (Alkeran) : 6 outcomes in 21 results : FDA 2 Generic
  3. Immunoglobulin G (IgG) : 5 outcomes 12 studies in 392 results : IBA
  4. bortezomib (Velcade) : 5 outcomes 1 study in 15 results : FDA 1
  5. Immunoglobulin M (IgM) : 4 outcomes 29 studies in 540 results : IBA
  6. Immunoglobulins (Immunoglobulin) : 4 outcomes 7 studies in 261 results : IBA
  7. Intravenous Immunoglobulins (IVIG) : 4 outcomes 3 studies in 19 results : FDA 1
  8. Amyloid (Amyloid Fibrils) : 3 outcomes 3 studies in 89 results : IBA
  9. Dexamethasone (Maxidex) : 3 outcomes 1 study in 18 results : FDA 77 Generic
  10. Prednisone (Sone) : 3 outcomes 1 study in 11 results : FDA 119 Generic
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Diseases Related to Paraproteinemias

  1. Multiple Myeloma
  2. Amyloidosis
  3. Polyneuropathies (Polyneuropathy)
  4. Pemphigus (Pemphigus Vulgaris)
  5. Paraproteinemias (Monoclonal Gammopathy)
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Key Therapies for Paraproteinemias

Efficacy Chart >>
  1. Stem Cell Transplantation : 4 outcomes in 12 results
  2. Drug Therapy (Chemotherapy) : 3 outcomes in 38 results
  3. Transplants (Transplant) : 3 outcomes in 25 results
  4. Enzyme Replacement Therapy : 2 outcomes in 3 results
  5. Transplantation (Transplant Recipients) : 1 outcome in 16 results
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