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Optic Neuritis (Retrobulbar Neuritis) Summary

Description: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

Also Known As: Retrobulbar Neuritis; Anterior Optic Neuritis; Posterior Optic Neuritis; Anterior Optic Neuritides; Neuritides, Anterior Optic Show All >>

Networked: 1179 relevant articles (58 outcomes, 126 trials/studies) for this Disease

Key Drugs and Agents for Optic Neuritis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Adrenal Cortex Hormones (Corticosteroids) : 11 outcomes 12 studies in 87 results : IBA
  2. Retinaldehyde (Retinal) : 8 outcomes 18 studies in 177 results : IBA
  3. Methylprednisolone : 6 outcomes 7 studies in 46 results : FDA 18 Generic
  4. Steroids : 3 outcomes 5 studies in 25 results : IBA
  5. Prednisolone (Predate) : 3 outcomes 5 studies in 15 results : FDA 55 Generic
  6. Immunoglobulins (Immunoglobulin) : 3 outcomes 3 studies in 13 results : IBA
  7. Erythropoietin : 2 outcomes 4 studies in 5 results : FDA 1
  8. Immunoglobulin G (IgG) : 2 outcomes 3 studies in 66 results : IBA
  9. Intravenous Immunoglobulins (IVIG) : 2 outcomes 1 study in 7 results : FDA 1
  10. Dexamethasone (Maxidex) : 2 outcomes 1 study in 7 results : FDA 77 Generic
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Diseases Related to Optic Neuritis

  1. Multiple Sclerosis
  2. Transverse Myelitis (Necrotizing Myelitis)
  3. Neuromyelitis Optica (Devic's Disease)
  4. Optic Nerve Diseases (Optic Neuropathy)
  5. Myasthenia Gravis
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Key Therapies for Optic Neuritis

Efficacy Chart >>
  1. Plasma Exchange : 2 outcomes 1 study in 10 results
  2. Decompression : 1 outcome 2 studies in 5 results
  3. Aftercare (After-Treatment) : 1 outcome 1 study in 16 results
  4. Immunomodulation : 1 outcome 1 study in 4 results
  5. Oral Administration : 1 outcome 1 study in 2 results
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