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Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy) Summary

Description: A group of inherited and sporadic disorders which share progressive ataxia in combination with atrophy of the CEREBELLUM; PONS; and inferior olivary nuclei. Additional clinical features may include MUSCLE RIGIDITY; NYSTAGMUS, PATHOLOGIC; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; and OPHTHALMOPLEGIA. The familial form has an earlier onset (second decade) and may feature spinal cord atrophy. The sporadic form tends to present in the fifth or sixth decade, and is considered a clinical subtype of MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)

Also Known As: Olivopontocerebellar Atrophy; Olivopontocerebellar Degeneration; Familial Olivopontocerebellar Atrophy; Inherited Olivopontocerebellar Atrophy; Nonfamilial Olivopontocerebellar Atrophy Show All >>

Networked: 166 relevant articles (4 outcomes, 17 trials/studies) for this Disease

Key Drugs and Agents for Olivopontocerebellar Atrophies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Dopamine (Intropin) : 1 outcome 1 study in 6 results : FDA 36 Generic
  2. Buspirone (Buspar) : 1 outcome 1 study in 2 results : FDA 16 Generic
  3. Glutamate Receptors (Glutamate Receptor) : 1 outcome in 4 results : IBA
  4. Amantadine (Aman) : 1 outcome in 3 results : FDA 20 Generic
  5. Thyrotropin-Releasing Hormone (Protirelin) : 1 outcome in 2 results : FDA 2
  6. N-Methylaspartate (NMDA) : 1 outcome in 1 result : IBA
  7. 5-Hydroxytryptophan (5 Hydroxytryptophan) : 1 outcome in 1 result : IBA
  8. Estrogens (Estrogen) : 1 outcome in 1 result : FDA 1
  9. Silver : 2 studies in 6 results : IBA
  10. Glucose (Dextrose) : 2 studies in 6 results : FDA 175 Generic
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Diseases Related to Olivopontocerebellar Atrophies

  1. Atrophy
  2. Multiple System Atrophy
  3. Friedreich Ataxia (Friedreich's Ataxia)
  4. Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy)
  5. Striatonigral Degeneration
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Key Therapies for Olivopontocerebellar Atrophies

Efficacy Chart >>
  1. Tracheostomy : 1 result
  2. Vaginal Hysterectomy : 1 result
  3. Cholecystectomy : 1 result
  4. Anesthesia : 1 result

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