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Nordihydroguaiaretic Acid (Masoprocol) Summary

Description: A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.

Also Known As: Masoprocol; Actinex; 4,4'-(2,3 Dimethyl-1,4-butanediyl)bis(1,2-benzenediol); Dihydronorguaiaretic Acid; Nordihydroguaiaretic Acid, (R*,S*)-Isomer Show All >>

Networked: 179 relevant articles (9 outcomes, 25 trials/studies) for this Drug

Key Diseases for which Nordihydroguaiaretic Acid is Relevant

  1. Neoplasms (Cancer) : 3 outcomes 6 studies in 48 results
  2. Inflammation : 1 outcome 2 studies in 11 results
  3. Breast Neoplasms (Breast Cancer) : 1 outcome 2 studies in 10 results
  4. Prostatic Neoplasms (Prostate Cancer) : 1 outcome 2 studies in 6 results
  5. Actinic Keratosis : 1 outcome 1 study in 2 results
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Drugs Related to Nordihydroguaiaretic Acid

  1. Lipoxygenase (Lipoxygenase-1)
  2. Arachidonic Acid (Vitamin F)
  3. Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
  4. Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
  5. 5,8,11,14-Eicosatetraynoic Acid (5,8,11,14 Eicosatetraynoic Acid)
  6. Hormones
  7. 4,5- Dihydro- 1- (3- (trifluoromethyl)phenyl)- 1H- pyrazol- 3- amine
  8. phenidone
  9. Lipoxygenase Inhibitors
  10. Potassium
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Therapies Related to Nordihydroguaiaretic Acid

  1. Transplantation (Transplant Recipients)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Radiotherapy
  4. Continuous Ambulatory Peritoneal Dialysis (CAPD)
  5. Ligation
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