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Wilms Tumor (Wilm's Tumor) Summary

Description: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.

Also Known As: Wilm's Tumor; Nephroblastoma; Wilms' Tumor; Nephroblastomas; Tumor, Bilateral Wilms Show All >>

Networked: 2674 relevant articles (80 outcomes, 284 trials/studies) for this Disease

Key Drugs and Agents for Wilms Tumor

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Dactinomycin (Ac-De) : 6 outcomes 22 studies in 93 results : FDA 2 Generic
  2. Vincristine (Oncovin) : 4 outcomes 15 studies in 70 results : FDA 17 Generic
  3. Etoposide (VP 16) : 4 outcomes 5 studies in 20 results : FDA 16 Generic
  4. Carboplatin (JM8) : 3 outcomes 5 studies in 13 results : FDA 29 Generic
  5. Antigens : 2 outcomes 11 studies in 131 results : IBA
  6. Messenger RNA (mRNA) : 2 outcomes 7 studies in 97 results : IBA
  7. Ifosfamide : 2 outcomes 3 studies in 17 results : FDA 7 Generic
  8. WT1 Proteins : 1 outcome 11 studies in 154 results : IBA
  9. Doxorubicin (Adriamycin) : 1 outcome 9 studies in 34 results : FDA 12 Generic
  10. DNA (Deoxyribonucleic Acid) : 1 outcome 6 studies in 97 results : IBA
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Diseases Related to Wilms Tumor

  1. Neoplasms (Cancer)
  2. Wilms Tumor (Wilm's Tumor)
  3. Leukemia
  4. Neoplasm Metastasis (Metastasis)
  5. Rhabdomyosarcoma
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Key Therapies for Wilms Tumor

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 29 outcomes 76 studies in 469 results
  2. Nephrectomy : 8 outcomes 37 studies in 293 results
  3. Radiotherapy : 7 outcomes 16 studies in 109 results
  4. Immunotherapy : 6 outcomes 5 studies in 53 results
  5. Combination Drug Therapy (Combination Chemotherapy) : 3 outcomes 1 study in 14 results
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