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Myoclonus (Nocturnal Myoclonus) Summary

Description: Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3).

Also Known As: Nocturnal Myoclonus; Myoclonic Jerk; Myoclonus, Sleep; Myoclonic Jerking; Myoclonus Simplex Show All >>

Networked: 1692 relevant articles (151 outcomes, 113 trials/studies) for this Disease

Key Drugs and Agents for Myoclonus

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Clonazepam (Rivotril) : 26 outcomes 5 studies in 98 results : FDA 16 Generic
  2. Piracetam (Nootropil) : 17 outcomes 8 studies in 33 results : IBA
  3. Valproic Acid (Valproate, Semisodium) : 16 outcomes 3 studies in 75 results : FDA 51 Generic
  4. etiracetam (levetiracetam) : 13 outcomes 8 studies in 42 results : FDA 45 Generic
  5. Etomidate : 7 outcomes 11 studies in 61 results : FDA 5 Generic
  6. Benzodiazepines : 7 outcomes 3 studies in 37 results : IBA
  7. Botulinum Toxins (Botulinum Toxin) : 6 outcomes 1 study in 24 results : IBA
  8. Carbidopa (Lodosyn) : 5 outcomes 1 study in 18 results : FDA 29 Generic
  9. 5-Hydroxytryptophan (5 Hydroxytryptophan) : 5 outcomes in 36 results : IBA
  10. Carbamazepine (Tegretol) : 4 outcomes 1 study in 34 results : FDA 24 Generic
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Diseases Related to Myoclonus

  1. Seizures (Seizure)
  2. Dystonia (Limb Dystonia)
  3. Myoclonus (Nocturnal Myoclonus)
  4. Tremor (Tremors)
  5. Movement Disorders (Movement Disorder)
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Key Therapies for Myoclonus

Efficacy Chart >>
  1. Deep Brain Stimulation : 7 outcomes 1 study in 23 results
  2. Anesthesia : 3 outcomes 1 study in 28 results
  3. Injections : 2 outcomes in 18 results
  4. Drug Therapy (Chemotherapy) : 2 outcomes in 11 results
  5. General Anesthesia : 2 outcomes in 4 results
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