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Myelodysplastic Syndromes (Myelodysplastic Syndrome) Summary

Description: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.

Also Known As: Myelodysplastic Syndrome; Hematopoetic Myelodysplasia; Dysmyelopoietic Syndrome; Hematopoetic Myelodysplasias; Myelodysplasia, Hematopoetic Show All >>

Networked: 5181 relevant articles (385 outcomes, 676 trials/studies) for this Disease

Key Drugs and Agents for Myelodysplastic Syndromes

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Azacitidine (5 Azacytidine) : 36 outcomes 58 studies in 323 results : FDA 1
  2. lenalidomide (CC 5013) : 31 outcomes 28 studies in 192 results : FDA 2
  3. Cytarabine (Cytosar-U) : 28 outcomes 54 studies in 246 results : FDA 13 Generic
  4. Erythropoietin : 23 outcomes 33 studies in 180 results : FDA 1
  5. decitabine (5-aza-2'-deoxycytidine) : 21 outcomes 37 studies in 203 results : FDA 1
  6. Granulocyte Colony-Stimulating Factor (G-CSF) : 18 outcomes 37 studies in 203 results : IBA
  7. Thalidomide (Thalomid) : 14 outcomes 13 studies in 78 results : FDA 2
  8. fludarabine : 13 outcomes 9 studies in 79 results : IBA
  9. Cyclosporine (Ciclosporin) : 13 outcomes 9 studies in 62 results : FDA 20 Generic
  10. DNA (Deoxyribonucleic Acid) : 9 outcomes 11 studies in 156 results : IBA
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Diseases Related to Myelodysplastic Syndromes

  1. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
  2. Anemia
  3. Leukemia
  4. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
  5. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
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Key Therapies for Myelodysplastic Syndromes

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 47 outcomes 52 studies in 436 results
  2. Hematopoietic Stem Cell Transplantation : 18 outcomes 16 studies in 168 results
  3. Transplantation (Transplant Recipients) : 14 outcomes 16 studies in 183 results
  4. Transplants (Transplant) : 12 outcomes 11 studies in 185 results
  5. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 11 outcomes 11 studies in 162 results
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