Search Login Register

Spinal Muscular Atrophy (Progressive Muscular Atrophy) Summary

Description: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

Also Known As: Progressive Muscular Atrophy; Adult Spinal Muscular Atrophy; Distal Spinal Muscular Atrophy; Spinal Muscular Atrophy, Distal; Muscular Atrophy, Spinal Show All >>

Networked: 757 relevant articles (19 outcomes, 56 trials/studies) for this Disease

Key Drugs and Agents for Spinal Muscular Atrophy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Histone Deacetylase Inhibitors : 2 outcomes 2 studies in 13 results : IBA
  2. Thyrotropin-Releasing Hormone (Protirelin) : 2 outcomes 1 study in 3 results : FDA 2
  3. Valproic Acid (Valproate, Semisodium) : 1 outcome 5 studies in 15 results : FDA 51 Generic
  4. gabapentin (Neurontin) : 1 outcome 2 studies in 2 results : FDA 37 Generic
  5. Antisense Oligonucleotides : 1 outcome 1 study in 5 results : IBA
  6. Hydroxyurea (Hydrea) : 1 outcome 1 study in 3 results : FDA 6 Generic
  7. Oxyhemoglobins (Oxyhemoglobin) : 1 outcome 1 study in 2 results : IBA
  8. Insulin (Novolin) : 1 outcome 1 study in 2 results : FDA 2
  9. RNA Precursors (Precursor, mRNA) : 1 outcome in 13 results : IBA
  10. plastin : 1 outcome in 6 results : IBA
Show All >>

Diseases Related to Spinal Muscular Atrophy

  1. Disease Progression
  2. Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
  3. Huntington Disease (Huntington's Disease)
  4. Neurodegenerative Diseases (Neurodegenerative Disease)
  5. Muscular Dystrophies (Muscular Dystrophy)
Show All >>

Key Therapies for Spinal Muscular Atrophy

Efficacy Chart >>
  1. Walkers : 1 outcome 1 study in 2 results
  2. Intravenous Injections : 1 outcome in 1 result
  3. Oral Administration : 1 outcome in 1 result
  4. Mechanical Ventilators (Ventilator) : 2 studies in 9 results
  5. Therapeutics : 1 study in 16 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.