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Multiple Myeloma Summary

Description: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Also Known As: Kahler Disease; Myeloma-Multiple; Myelomatosis; Plasma Cell Myeloma; Cell Myeloma, Plasma Show All >>

Networked: 14060 relevant articles (1172 outcomes, 2130 trials/studies) for this Disease

Key Drugs and Agents for Multiple Myeloma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. bortezomib (Velcade) : 265 outcomes 349 studies in 1658 results : FDA 1
  2. Thalidomide (Thalomid) : 191 outcomes 201 studies in 1014 results : FDA 2
  3. Dexamethasone (Maxidex) : 128 outcomes 245 studies in 890 results : FDA 77 Generic
  4. lenalidomide (CC 5013) : 123 outcomes 149 studies in 718 results : FDA 2
  5. Proteasome Endopeptidase Complex (Proteasome) : 84 outcomes 74 studies in 693 results : IBA
  6. Melphalan (Alkeran) : 82 outcomes 199 studies in 811 results : FDA 2 Generic
  7. Cyclophosphamide (Cytoxan) : 44 outcomes 87 studies in 363 results : FDA 10 Generic
  8. Prednisone (Sone) : 37 outcomes 117 studies in 314 results : FDA 119 Generic
  9. Doxorubicin (Adriamycin) : 32 outcomes 62 studies in 270 results : FDA 12 Generic
  10. Vincristine (Oncovin) : 27 outcomes 60 studies in 230 results : FDA 17 Generic
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Diseases Related to Multiple Myeloma

  1. Neoplasms (Cancer)
  2. Non-Hodgkin Lymphoma (Lymphosarcoma)
  3. Neoplasm Metastasis (Metastasis)
  4. Breast Neoplasms (Breast Cancer)
  5. Lymphoma (Lymphomas)
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Key Therapies for Multiple Myeloma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 137 outcomes 161 studies in 1313 results
  2. Stem Cell Transplantation : 112 outcomes 118 studies in 849 results
  3. Transplants (Transplant) : 43 outcomes 69 studies in 581 results
  4. Transplantation (Transplant Recipients) : 30 outcomes 42 studies in 310 results
  5. Combination Drug Therapy (Combination Chemotherapy) : 18 outcomes 27 studies in 127 results
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