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Metallothionein Summary

Description: A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.

Also Known As: Isometallothionein; Metallothionein A; Metallothionein B; Metallothionein I; Metallothionein II Show All >>

Networked: 1427 relevant articles (29 outcomes, 187 trials/studies) for this Bio-Agent

Key Diseases for which Metallothionein is Relevant

  1. Neoplasms (Cancer) : 6 outcomes 29 studies in 256 results
  2. Anoxia (Hypoxia) : 4 outcomes 6 studies in 38 results
  3. Ischemia : 3 outcomes 4 studies in 18 results
  4. Breast Neoplasms (Breast Cancer) : 2 outcomes 6 studies in 42 results
  5. Inflammation : 2 outcomes 4 studies in 67 results
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Drugs Related to Metallothionein

  1. Proteins (Proteins, Gene)
  2. Zinc
  3. P-Glycoprotein
  4. Protein Isoforms (Isoforms)
  5. Cytokines
  6. Glutathione S-Transferase pi
  7. Glutathione Transferase (Glutathione S-Transferase)
  8. Cytochrome P-450 Enzyme System (Cytochrome P450)
  9. NG-Nitroarginine Methyl Ester (L-NAME)
  10. Ions
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Therapies Related to Metallothionein

  1. Drug Therapy (Chemotherapy)
  2. Injections
  3. Homologous Transplantation (Allograft)
  4. Transplants (Transplant)
  5. Nephrectomy
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