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Medulloblastoma Summary

Description: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)

Also Known As: Medulloblastoma, Adult; Medulloblastoma, Childhood; Melanocytic Medulloblastoma; Adult Medulloblastoma; Adult Medulloblastomas Show All >>

Networked: 2504 relevant articles (132 outcomes, 380 trials/studies) for this Disease

Key Drugs and Agents for Medulloblastoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Vincristine (Oncovin) : 10 outcomes 13 studies in 59 results : FDA 17 Generic
  2. Cisplatin (Platino) : 6 outcomes 12 studies in 74 results : FDA 6 Generic
  3. Etoposide (VP 16) : 5 outcomes 11 studies in 61 results : FDA 16 Generic
  4. Cyclophosphamide (Cytoxan) : 4 outcomes 8 studies in 34 results : FDA 10 Generic
  5. Methotrexate (Mexate) : 4 outcomes 6 studies in 26 results : FDA 8 Generic
  6. Lomustine (CCNU) : 4 outcomes 3 studies in 23 results : FDA 1
  7. Procarbazine (Matulane) : 3 outcomes 4 studies in 18 results : FDA 1
  8. Carboplatin (JM8) : 2 outcomes 9 studies in 28 results : FDA 29 Generic
  9. DNA (Deoxyribonucleic Acid) : 2 outcomes 6 studies in 103 results : IBA
  10. resveratrol : 2 outcomes 5 studies in 12 results : IBA
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Diseases Related to Medulloblastoma

  1. Neoplasms (Cancer)
  2. Primitive Neuroectodermal Tumors (PNET)
  3. Brain Neoplasms (Brain Tumor)
  4. Astrocytoma (Pilocytic Astrocytoma)
  5. Neoplasm Metastasis (Metastasis)
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Key Therapies for Medulloblastoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 48 outcomes 69 studies in 447 results
  2. Radiotherapy : 23 outcomes 51 studies in 309 results
  3. Heterologous Transplantation (Xenotransplantation) : 8 outcomes 18 studies in 110 results
  4. Adjuvant Chemotherapy : 4 outcomes 15 studies in 61 results
  5. Combination Drug Therapy (Combination Chemotherapy) : 3 outcomes in 15 results
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